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KIMIA FENBENDAZOLE 2.5® (FENBENDAZOLE 2.5% ):
Fenbendazole is as inhibitor of fumarate reductase. Blockage of enzyme step inhibits generation of mitochondrial energy in the form of ATP. In the absence of usable energy the parasite dies. The drug is not well absorbed in the intestine, the peak plasma level occurs in 10-12 hours. Approximately 90% of the drug is excreted in the feces and some unchanged drug is excreted in the urine.
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